Cystic Fibrosis Forum (EXP)

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Recent content by marcob

  1. M

    Kalydeco and Class IV Mutations

    GenH, Now it's a matter of months for you, this is really encouraging. Wish you all the best. I think all the time about this treatment and hope it can also work for us... There are so many mutations that I hope they will choose a different approach soon, I mean, if the drug is safe why don't we...
  2. M

    Kalydeco and Class IV Mutations

    They are pancreatic sufficient and the doc told me 4 or 5 for the class. Yes it's extremely rare, my wife is Thai with chinese origins. They took many months to identify it. I would be more than happy if kalydeco could help. I assume you are on it based on your mutation, is it?
  3. M

    Kalydeco and Class IV Mutations

    GenH, Thanks a lot for your reply this is very clear. G970D is maybe 4 or 5, the doctor wasn't sure. Hopefully the 3D structure won't be too far from the G970R...
  4. M

    Kalydeco and Class IV Mutations

    Hi, Can someone explain the main difference in mutation regarding the last letter? What the latest letter means exactly? I've got almost the same question mark at my side. My son is G970D and it seems that G970R is in the list of potential candidates for VX770. How far are the mutations ? Thanks...
  5. M

    Kalydeco or VX-770 off lable use?

    this can interest you maybe <a href="http://saltyspark.blogspot.com/2012/03/kalydeco-for-class-i-and-class-ii.html">http://saltyspark.blogspot.com/2012/03/kalydeco-for-class-i-and-class-ii.html</a>
  6. M

    Kalydeco or VX-770 off lable use?

    this can interest you maybe <a href="http://saltyspark.blogspot.com/2012/03/kalydeco-for-class-i-and-class-ii.html">http://saltyspark.blogspot.com/2012/03/kalydeco-for-class-i-and-class-ii.html</a>
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