Hi, I battled ABPA for 4 yrs. The steriods are the main treatment, unfortunately. If you have a lot of problems with the prednisone, maybe you could try medrol, another steriod. How long were you on the itraconazale for? It usually takes at least 6 mos. to work, or at least that's what they told me. But there is a light at the end of the tunnel. I was last on steriods for ABPA 5 years ago, and it has been under control ever since <img src="i/expressions/face-icon-small-happy.gif" border="0"> Just out of curiosity, what was your IgE? Mine went as high 1700 at one point. Good Luck~ Mary