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HELP!!!!!

Zoey7206

New member
What does 46 XX mean? It has this in parenthesis on zoeys discharge summary under cystic fibrosis. It also says she has two mutations of the cftr gene. By the way ZOEYS HOME!!!!!!!!!!!!!!!!!!!!!!!! She got to come home the 16th. And we have been busy. She is still on tpn and lipids for 14 hours a day. Ill have to upload pics later
 

Zoey7206

New member
What does 46 XX mean? It has this in parenthesis on zoeys discharge summary under cystic fibrosis. It also says she has two mutations of the cftr gene. By the way ZOEYS HOME!!!!!!!!!!!!!!!!!!!!!!!! She got to come home the 16th. And we have been busy. She is still on tpn and lipids for 14 hours a day. Ill have to upload pics later
 

Zoey7206

New member
What does 46 XX mean? It has this in parenthesis on zoeys discharge summary under cystic fibrosis. It also says she has two mutations of the cftr gene. By the way ZOEYS HOME!!!!!!!!!!!!!!!!!!!!!!!! She got to come home the 16th. And we have been busy. She is still on tpn and lipids for 14 hours a day. Ill have to upload pics later
 

littledebbie

New member
I tried googling different variations of that...the best I can see XX might indicate -female. Where XY would be male? But as to 46 XX....? Maybe one of our more medical savy people will have a clue <img src="i/expressions/face-icon-small-smile.gif" border="0">
 

littledebbie

New member
I tried googling different variations of that...the best I can see XX might indicate -female. Where XY would be male? But as to 46 XX....? Maybe one of our more medical savy people will have a clue <img src="i/expressions/face-icon-small-smile.gif" border="0">
 

littledebbie

New member
I tried googling different variations of that...the best I can see XX might indicate -female. Where XY would be male? But as to 46 XX....? Maybe one of our more medical savy people will have a clue <img src="i/expressions/face-icon-small-smile.gif" border="0">
 
J

Jade

Guest
<i>This is all I could find relating to your question. Probably not much help though. I'd just call the doctors and ask</i>.

<b>Each normal human being has 46 chromosomes, in 23 pairs, including a pair of "sex chromosomes." A normal male has one X and one Y chromosome (46XY karyotype) and a normal female has two X chromosomes (46XX karyotype). Each embryo receives an X chromosome from the mother and either an X or a Y chromosome from the father, via the sperm. Some individuals are born with an abnormal number of chromosomes, a condition called "aneuploidy." For example, if there are 3 sets of the non-sex chromosome 21 instead of a pair, this particular type of aneuploidy is known as Trisomy 21 or Downs syndrome. An individual may be born with an abnormal number of the sex chromosomes. These "sex chromosome aneuploidies" will have different characteristics in the offspring depending on which chromosome is abnormal. The embryo can have a missing X chromosome (45X karyotype) or an extra X or extra Y chromosome (47XXY, 47XYY, 47XXX karyotypes). Different types of abnormalities in the offspring can occur, depending on the type of aneuploidy.


The risk of a sex chromosome abnormality in the general population (natural conceptions) is about 2 in every 1000 births (0.2%). The first studies reporting on follow-up of first few hundred children born after ICSI did not find any statistically significant differences between ICSI-conceived babies and other IVF or naturally-conceived babies. However, in 1995, two studies were published that suggested there may be a slight increase in sex chromosome abnormalities in ICSI-conceived children. The most recent update from the Belgium group combined with other studies which in total have reported genetic results from 2083 children conceived after IVF-ICSI report that the risk of a sex chromosome abnormality in children born after IVF with ICSI is about 7 in every 1000 births (0.7%). It is unclear if this increased risk is more likely to be seen in men with very severe sperm defects who would otherwise have no chance of conceiving their own genetic child without IVF-ICSI, or whether there is something about the sperm injection procedure itself that may lead to this slightly increased risk. That is, there may be something about the sperm of fathers with very low sperm counts that inherently leads to the increased risk in their children. Most of the men undergoing ICSI in Belgium are men with extremely low sperm counts, many of whom who must undergo testicular biopsy to obtain sperm for the injection process. Men with a history of proven fertility, such as men undergoing IVF-ICSI because of a prior vasectomy, may be in a different risk group. Further studies will be needed to clarify this issue. </b>
 
J

Jade

Guest
<i>This is all I could find relating to your question. Probably not much help though. I'd just call the doctors and ask</i>.

<b>Each normal human being has 46 chromosomes, in 23 pairs, including a pair of "sex chromosomes." A normal male has one X and one Y chromosome (46XY karyotype) and a normal female has two X chromosomes (46XX karyotype). Each embryo receives an X chromosome from the mother and either an X or a Y chromosome from the father, via the sperm. Some individuals are born with an abnormal number of chromosomes, a condition called "aneuploidy." For example, if there are 3 sets of the non-sex chromosome 21 instead of a pair, this particular type of aneuploidy is known as Trisomy 21 or Downs syndrome. An individual may be born with an abnormal number of the sex chromosomes. These "sex chromosome aneuploidies" will have different characteristics in the offspring depending on which chromosome is abnormal. The embryo can have a missing X chromosome (45X karyotype) or an extra X or extra Y chromosome (47XXY, 47XYY, 47XXX karyotypes). Different types of abnormalities in the offspring can occur, depending on the type of aneuploidy.


The risk of a sex chromosome abnormality in the general population (natural conceptions) is about 2 in every 1000 births (0.2%). The first studies reporting on follow-up of first few hundred children born after ICSI did not find any statistically significant differences between ICSI-conceived babies and other IVF or naturally-conceived babies. However, in 1995, two studies were published that suggested there may be a slight increase in sex chromosome abnormalities in ICSI-conceived children. The most recent update from the Belgium group combined with other studies which in total have reported genetic results from 2083 children conceived after IVF-ICSI report that the risk of a sex chromosome abnormality in children born after IVF with ICSI is about 7 in every 1000 births (0.7%). It is unclear if this increased risk is more likely to be seen in men with very severe sperm defects who would otherwise have no chance of conceiving their own genetic child without IVF-ICSI, or whether there is something about the sperm injection procedure itself that may lead to this slightly increased risk. That is, there may be something about the sperm of fathers with very low sperm counts that inherently leads to the increased risk in their children. Most of the men undergoing ICSI in Belgium are men with extremely low sperm counts, many of whom who must undergo testicular biopsy to obtain sperm for the injection process. Men with a history of proven fertility, such as men undergoing IVF-ICSI because of a prior vasectomy, may be in a different risk group. Further studies will be needed to clarify this issue. </b>
 
J

Jade

Guest
<i>This is all I could find relating to your question. Probably not much help though. I'd just call the doctors and ask</i>.

<b>Each normal human being has 46 chromosomes, in 23 pairs, including a pair of "sex chromosomes." A normal male has one X and one Y chromosome (46XY karyotype) and a normal female has two X chromosomes (46XX karyotype). Each embryo receives an X chromosome from the mother and either an X or a Y chromosome from the father, via the sperm. Some individuals are born with an abnormal number of chromosomes, a condition called "aneuploidy." For example, if there are 3 sets of the non-sex chromosome 21 instead of a pair, this particular type of aneuploidy is known as Trisomy 21 or Downs syndrome. An individual may be born with an abnormal number of the sex chromosomes. These "sex chromosome aneuploidies" will have different characteristics in the offspring depending on which chromosome is abnormal. The embryo can have a missing X chromosome (45X karyotype) or an extra X or extra Y chromosome (47XXY, 47XYY, 47XXX karyotypes). Different types of abnormalities in the offspring can occur, depending on the type of aneuploidy.


The risk of a sex chromosome abnormality in the general population (natural conceptions) is about 2 in every 1000 births (0.2%). The first studies reporting on follow-up of first few hundred children born after ICSI did not find any statistically significant differences between ICSI-conceived babies and other IVF or naturally-conceived babies. However, in 1995, two studies were published that suggested there may be a slight increase in sex chromosome abnormalities in ICSI-conceived children. The most recent update from the Belgium group combined with other studies which in total have reported genetic results from 2083 children conceived after IVF-ICSI report that the risk of a sex chromosome abnormality in children born after IVF with ICSI is about 7 in every 1000 births (0.7%). It is unclear if this increased risk is more likely to be seen in men with very severe sperm defects who would otherwise have no chance of conceiving their own genetic child without IVF-ICSI, or whether there is something about the sperm injection procedure itself that may lead to this slightly increased risk. That is, there may be something about the sperm of fathers with very low sperm counts that inherently leads to the increased risk in their children. Most of the men undergoing ICSI in Belgium are men with extremely low sperm counts, many of whom who must undergo testicular biopsy to obtain sperm for the injection process. Men with a history of proven fertility, such as men undergoing IVF-ICSI because of a prior vasectomy, may be in a different risk group. Further studies will be needed to clarify this issue. </b>
 

julie

New member
It means she has 46 chromosomes (more or less could mean a different disease, Downs syndrome for example) and XX means she's a girl.

Glad to hear that she is home!!!!!!!!!!
 

julie

New member
It means she has 46 chromosomes (more or less could mean a different disease, Downs syndrome for example) and XX means she's a girl.

Glad to hear that she is home!!!!!!!!!!
 

julie

New member
It means she has 46 chromosomes (more or less could mean a different disease, Downs syndrome for example) and XX means she's a girl.

Glad to hear that she is home!!!!!!!!!!
 
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