I believe there's a certain order to the meds -- bronchiodialators to open things up, get things moving up and out. Pulmozyme to thin the mucus. With Tobi, you want to make sure that it stays in the lungs for awhile, so we always do it after CPT and albuterol/atrovent. We do pulmozyme during a separate treatment -- the last one of the evening before bed.