Be prepared to answer plenty of annoying questions at the airport of you're checking compressors, etc! Make sure you have the appropriate outlet adapters so your equipment works (check to see if you need voltage converters, as well). Depending on how paranoid you are about recycled airplane air, you might want a mask. The thing I found most difficult was making time for treatments and taking care of myself. It was too easy to get caught up in the fun and business of the trip, and my health suffered. Also, after my trip to France, I began culturing a new, resistant fungus that my doctor says I had to have picked up somewhere. It's not definite that it was my trip, but that was the only thing out of the ordinary. Beware of hotel showers!