Wow, how disappointing to hear all thnegative statements. Hope is the key. The Foundations do help, where would we be without them? It does cost money to get things done. I suggest going to some yearly meetings the doctors usually have with updates with CF. They will tell yo their progress an what they are trying next. My daughter was born right when Pulmozyme became available. She was 5 when she got to use it and she is doing excellent. Some of the problems are those nasty germs, we work so hard to stay away from. Stay away from rotting vegetables. Especially onions. Do that vest. Yeah it itches but you will build a tolerance to it. My daughter is 22 and I can count on my fingers, the number of times she skipped a whole day of treatment. Overkill is better than leaving treatments out. When she was a baby, we did overkill. She is developing diabetes but follow those doctor's advice. She has one of the strong genes and one mutation. She needs her 5 enzymes to digest her food. She is a happy person. No need to see the bad in everything. She loves life and you cant do that unless you want it. We think she is going to live until her 60's and she doesn't have a mild case. If she does skip her treatments, just one day, she always gets sick with an infection. I pray that the negative people can find the joy in life and not worry when they are going to die. We can all get hit by a car tomorrow.