I have an unborn daughter coming in the Summer who has the mutation.F405delta and 1717G1->AI have done some research and concluded that both of these mutations are associated with the severe disease (as far as the insufficient pancrease is concerned). Does anyone else have this mutation set? Is the pancreatic defficiency the cause of all of the GI issues like irritable bowels, diahrea, stomache pain? My wife and I have used your kind words of inspiration and bravery to prepare ourselves for the future. If our society faced its own mortality with one iota of clarity that members of this community does, we would have a much better world. Thanks, again.