What's new
Cystic Fibrosis Forum (EXP)

This is a sample guest message. Register a free account today to become a member! Once signed in, you'll be able to participate on this site by adding your own topics and posts, as well as connect with other members through your own private inbox!

?? about lung damage

JazzysMom

New member
For some reason my brain isnt working this morning so give me a jump start.

One of the concerns for some people going on ivs as maintenance rather then treat as it occurs is resistance to the antibiotics.

One of the answers given is that CFers dont die from drug resistance, we die from respiratory failure brought on by lung damage.

In my head I know preventive is the way to go yet a part of me is questioning whether the resistance contributes to death and does become more problematic with time.

If we are prone to MRSA, a few strands of PA and maybe Cepecia (and whatever else is out there) the more we are alive (statiscallly this would make sense to me....the longer alive the more chance of exposure) then wouldnt resistance to abx (from maintenance etc over time) be a bigger issue by not allowing the arsenal maybe available prior to any resistance which would in turn causie lung damage which in turn leads to death.

This sure sounds good in my head.....hope it makes sense to all of you.

AMY I am hoping to hear from you!!!!
 

JazzysMom

New member
For some reason my brain isnt working this morning so give me a jump start.

One of the concerns for some people going on ivs as maintenance rather then treat as it occurs is resistance to the antibiotics.

One of the answers given is that CFers dont die from drug resistance, we die from respiratory failure brought on by lung damage.

In my head I know preventive is the way to go yet a part of me is questioning whether the resistance contributes to death and does become more problematic with time.

If we are prone to MRSA, a few strands of PA and maybe Cepecia (and whatever else is out there) the more we are alive (statiscallly this would make sense to me....the longer alive the more chance of exposure) then wouldnt resistance to abx (from maintenance etc over time) be a bigger issue by not allowing the arsenal maybe available prior to any resistance which would in turn causie lung damage which in turn leads to death.

This sure sounds good in my head.....hope it makes sense to all of you.

AMY I am hoping to hear from you!!!!
 

JazzysMom

New member
For some reason my brain isnt working this morning so give me a jump start.

One of the concerns for some people going on ivs as maintenance rather then treat as it occurs is resistance to the antibiotics.

One of the answers given is that CFers dont die from drug resistance, we die from respiratory failure brought on by lung damage.

In my head I know preventive is the way to go yet a part of me is questioning whether the resistance contributes to death and does become more problematic with time.

If we are prone to MRSA, a few strands of PA and maybe Cepecia (and whatever else is out there) the more we are alive (statiscallly this would make sense to me....the longer alive the more chance of exposure) then wouldnt resistance to abx (from maintenance etc over time) be a bigger issue by not allowing the arsenal maybe available prior to any resistance which would in turn causie lung damage which in turn leads to death.

This sure sounds good in my head.....hope it makes sense to all of you.

AMY I am hoping to hear from you!!!!
 

JazzysMom

New member
For some reason my brain isnt working this morning so give me a jump start.

One of the concerns for some people going on ivs as maintenance rather then treat as it occurs is resistance to the antibiotics.

One of the answers given is that CFers dont die from drug resistance, we die from respiratory failure brought on by lung damage.

In my head I know preventive is the way to go yet a part of me is questioning whether the resistance contributes to death and does become more problematic with time.

If we are prone to MRSA, a few strands of PA and maybe Cepecia (and whatever else is out there) the more we are alive (statiscallly this would make sense to me....the longer alive the more chance of exposure) then wouldnt resistance to abx (from maintenance etc over time) be a bigger issue by not allowing the arsenal maybe available prior to any resistance which would in turn causie lung damage which in turn leads to death.

This sure sounds good in my head.....hope it makes sense to all of you.

AMY I am hoping to hear from you!!!!
 

JazzysMom

New member
For some reason my brain isnt working this morning so give me a jump start.

One of the concerns for some people going on ivs as maintenance rather then treat as it occurs is resistance to the antibiotics.

One of the answers given is that CFers dont die from drug resistance, we die from respiratory failure brought on by lung damage.

In my head I know preventive is the way to go yet a part of me is questioning whether the resistance contributes to death and does become more problematic with time.

If we are prone to MRSA, a few strands of PA and maybe Cepecia (and whatever else is out there) the more we are alive (statiscallly this would make sense to me....the longer alive the more chance of exposure) then wouldnt resistance to abx (from maintenance etc over time) be a bigger issue by not allowing the arsenal maybe available prior to any resistance which would in turn causie lung damage which in turn leads to death.

This sure sounds good in my head.....hope it makes sense to all of you.

AMY I am hoping to hear from you!!!!
 

JazzysMom

New member
For some reason my brain isnt working this morning so give me a jump start.

One of the concerns for some people going on ivs as maintenance rather then treat as it occurs is resistance to the antibiotics.

One of the answers given is that CFers dont die from drug resistance, we die from respiratory failure brought on by lung damage.

In my head I know preventive is the way to go yet a part of me is questioning whether the resistance contributes to death and does become more problematic with time.

If we are prone to MRSA, a few strands of PA and maybe Cepecia (and whatever else is out there) the more we are alive (statiscallly this would make sense to me....the longer alive the more chance of exposure) then wouldnt resistance to abx (from maintenance etc over time) be a bigger issue by not allowing the arsenal maybe available prior to any resistance which would in turn causie lung damage which in turn leads to death.

This sure sounds good in my head.....hope it makes sense to all of you.

AMY I am hoping to hear from you!!!!
 

NoExcuses

New member
But the point is, Mel, you're older.

That's the bottomline. As you said "as we get older couldn't resistance to abx be a bigger issue"

If you're not aggressive with abx, and your lungs deteriorate faster due to lack of abx treatment, you're not getting older. Or not nearly as old as you would be if you were aggressive with abx and risking resistance.

Take Denmark for example. Median life expectancy nearing 50. They have more resistance than most. Yes.

But you konw what? Median life expectancy is 50!!!!!!!!!!!!!!!

That's 10 years more than the US (save a few CF centers such as Minnesota).

So as you said earlier. What's the point of dying from low lung function being suseptable to most abx? Why not use your arsenal to try to live as long as possible?

I'd rather life to 50 being pan-resistant than live to 36.8 being suseptable to some abx.

Hope that makes sense.
 

NoExcuses

New member
But the point is, Mel, you're older.

That's the bottomline. As you said "as we get older couldn't resistance to abx be a bigger issue"

If you're not aggressive with abx, and your lungs deteriorate faster due to lack of abx treatment, you're not getting older. Or not nearly as old as you would be if you were aggressive with abx and risking resistance.

Take Denmark for example. Median life expectancy nearing 50. They have more resistance than most. Yes.

But you konw what? Median life expectancy is 50!!!!!!!!!!!!!!!

That's 10 years more than the US (save a few CF centers such as Minnesota).

So as you said earlier. What's the point of dying from low lung function being suseptable to most abx? Why not use your arsenal to try to live as long as possible?

I'd rather life to 50 being pan-resistant than live to 36.8 being suseptable to some abx.

Hope that makes sense.
 

NoExcuses

New member
But the point is, Mel, you're older.

That's the bottomline. As you said "as we get older couldn't resistance to abx be a bigger issue"

If you're not aggressive with abx, and your lungs deteriorate faster due to lack of abx treatment, you're not getting older. Or not nearly as old as you would be if you were aggressive with abx and risking resistance.

Take Denmark for example. Median life expectancy nearing 50. They have more resistance than most. Yes.

But you konw what? Median life expectancy is 50!!!!!!!!!!!!!!!

That's 10 years more than the US (save a few CF centers such as Minnesota).

So as you said earlier. What's the point of dying from low lung function being suseptable to most abx? Why not use your arsenal to try to live as long as possible?

I'd rather life to 50 being pan-resistant than live to 36.8 being suseptable to some abx.

Hope that makes sense.
 

NoExcuses

New member
But the point is, Mel, you're older.

That's the bottomline. As you said "as we get older couldn't resistance to abx be a bigger issue"

If you're not aggressive with abx, and your lungs deteriorate faster due to lack of abx treatment, you're not getting older. Or not nearly as old as you would be if you were aggressive with abx and risking resistance.

Take Denmark for example. Median life expectancy nearing 50. They have more resistance than most. Yes.

But you konw what? Median life expectancy is 50!!!!!!!!!!!!!!!

That's 10 years more than the US (save a few CF centers such as Minnesota).

So as you said earlier. What's the point of dying from low lung function being suseptable to most abx? Why not use your arsenal to try to live as long as possible?

I'd rather life to 50 being pan-resistant than live to 36.8 being suseptable to some abx.

Hope that makes sense.
 

NoExcuses

New member
But the point is, Mel, you're older.

That's the bottomline. As you said "as we get older couldn't resistance to abx be a bigger issue"

If you're not aggressive with abx, and your lungs deteriorate faster due to lack of abx treatment, you're not getting older. Or not nearly as old as you would be if you were aggressive with abx and risking resistance.

Take Denmark for example. Median life expectancy nearing 50. They have more resistance than most. Yes.

But you konw what? Median life expectancy is 50!!!!!!!!!!!!!!!

That's 10 years more than the US (save a few CF centers such as Minnesota).

So as you said earlier. What's the point of dying from low lung function being suseptable to most abx? Why not use your arsenal to try to live as long as possible?

I'd rather life to 50 being pan-resistant than live to 36.8 being suseptable to some abx.

Hope that makes sense.
 

NoExcuses

New member
But the point is, Mel, you're older.

That's the bottomline. As you said "as we get older couldn't resistance to abx be a bigger issue"

If you're not aggressive with abx, and your lungs deteriorate faster due to lack of abx treatment, you're not getting older. Or not nearly as old as you would be if you were aggressive with abx and risking resistance.

Take Denmark for example. Median life expectancy nearing 50. They have more resistance than most. Yes.

But you konw what? Median life expectancy is 50!!!!!!!!!!!!!!!

That's 10 years more than the US (save a few CF centers such as Minnesota).

So as you said earlier. What's the point of dying from low lung function being suseptable to most abx? Why not use your arsenal to try to live as long as possible?

I'd rather life to 50 being pan-resistant than live to 36.8 being suseptable to some abx.

Hope that makes sense.
 

JazzysMom

New member
I know this seemed like an obvious answer to you and it is, but for some reason my brain just wouldnt work.

THANKS........
 

JazzysMom

New member
I know this seemed like an obvious answer to you and it is, but for some reason my brain just wouldnt work.

THANKS........
 

JazzysMom

New member
I know this seemed like an obvious answer to you and it is, but for some reason my brain just wouldnt work.

THANKS........
 

JazzysMom

New member
I know this seemed like an obvious answer to you and it is, but for some reason my brain just wouldnt work.

THANKS........
 

JazzysMom

New member
I know this seemed like an obvious answer to you and it is, but for some reason my brain just wouldnt work.

THANKS........
 

JazzysMom

New member
I know this seemed like an obvious answer to you and it is, but for some reason my brain just wouldnt work.

THANKS........
 

NoExcuses

New member
I want to add one more thing:


let's say your FEV1 is 30% and your PA is suseptable to every possible abx in the world. You're probably not getting back up to 70%, even in that scenario.

But let's say you're at 70% and you're getting IV's every 3 months. What are the chances that you're going to catch any flare-ups and preserve lung function?

Sure, over the years, you're going to get resistance. But you'll probably stay stable for a good amount of time.

These scenarios don't always play out exactly like this of course. But they do more often than not, producing longer life spans.

And that's the bottomline <img src="i/expressions/face-icon-small-smile.gif" border="0">
 

NoExcuses

New member
I want to add one more thing:


let's say your FEV1 is 30% and your PA is suseptable to every possible abx in the world. You're probably not getting back up to 70%, even in that scenario.

But let's say you're at 70% and you're getting IV's every 3 months. What are the chances that you're going to catch any flare-ups and preserve lung function?

Sure, over the years, you're going to get resistance. But you'll probably stay stable for a good amount of time.

These scenarios don't always play out exactly like this of course. But they do more often than not, producing longer life spans.

And that's the bottomline <img src="i/expressions/face-icon-small-smile.gif" border="0">
 
Top