Albuterol ?'s

[kswitch]

<div class="FTQUOTE"><begin quote><i>Originally posted by: <b>sakasuka</b></i>

<div class="FTQUOTE"><begin quote><i>Originally posted by: <b>kswitch</b></i>



i'm no doc, but i do know that tolerance is a mental state.



</end quote></div>



That is far from the truth, to put it lightly.



Tolerance is not mental, it's physical. There are physiological changes that occure in the body when a tolerance is built up to a medical.





<div class="FTQUOTE"><begin quote> when we first start using a drug, the effects can be profound. as this profoundness wears off, they can feel less effective as the brain compensates for the altered state. </end quote></div>





not sure where you got that from, but again, this is flat out false.</end quote></div>


i get that from my experience, and readings into addiction. what kind of physiological changes might be occuring that make a drug less effective? chemical reactions don't build a tolerance and happen less efficiently without physical or chemical change. i don't dispute that it's possible, but what i question is whether the effect is due to the properties of the drug itself, or some other environmental factor.

if i am wrong, please enlighten me with an informative response rather than an antagonistic one. you're not helping me understand a lick, but i hope you feel better. is my medical knowledge not academic enough to partake of your infinite wisdom? or is your knowledge as opinionated and experientially obtained as mine is?

 

[ladybug]

I am on albuterol in the AM and duoneb in the evening. I used to use albuterol at night and mix it myself with atrovent which was crazy since there is a product for this! LOL...

I too heard that atrovent can dry secretions when I stitched to this new CF doc (my prior CF doc put me on it in another state)... But, she said I can feel free to stay on it if I want. I don't really see any difference personally, so I stayed on it cause I'm afraid of change. LOL

Anyway, I don't know how tolerance would work with CF drugs. I suppose maybe something like "resistance", which happens with overusing particular antibiotics, but as far as things that aim to open the airways, and have nothing to do with your infections directly, I don't know if your lungs would "get used to" something that has just one thing to do ... to open you up. I don't really see how that could happen with something like albuterol. I can see how you'd get sicker or have bad days when you didn't feel it helped you as much so need it more often, but that's all I've heard of.

I do know tolerance IS a real thing with regards to some psychological drugs, etc. where you'd need more of the med to get the same benefit the longer you use it, but it only happens with some drugs and I don't think things like bronchodialators fall into that category. I don't think we really have to worry about it much with things like inhaled meds. I think if you need something more or aren't feeling its effects, maybe your lungs just aren't where they were before and need more of the med to really open you up. I don't know...

Sorry for the long-winded answer. Its late. LOL

 

[ladybug]

I am on albuterol in the AM and duoneb in the evening. I used to use albuterol at night and mix it myself with atrovent which was crazy since there is a product for this! LOL...

I too heard that atrovent can dry secretions when I stitched to this new CF doc (my prior CF doc put me on it in another state)... But, she said I can feel free to stay on it if I want. I don't really see any difference personally, so I stayed on it cause I'm afraid of change. LOL

Anyway, I don't know how tolerance would work with CF drugs. I suppose maybe something like "resistance", which happens with overusing particular antibiotics, but as far as things that aim to open the airways, and have nothing to do with your infections directly, I don't know if your lungs would "get used to" something that has just one thing to do ... to open you up. I don't really see how that could happen with something like albuterol. I can see how you'd get sicker or have bad days when you didn't feel it helped you as much so need it more often, but that's all I've heard of.

I do know tolerance IS a real thing with regards to some psychological drugs, etc. where you'd need more of the med to get the same benefit the longer you use it, but it only happens with some drugs and I don't think things like bronchodialators fall into that category. I don't think we really have to worry about it much with things like inhaled meds. I think if you need something more or aren't feeling its effects, maybe your lungs just aren't where they were before and need more of the med to really open you up. I don't know...

Sorry for the long-winded answer. Its late. LOL

 

[ladybug]

I am on albuterol in the AM and duoneb in the evening. I used to use albuterol at night and mix it myself with atrovent which was crazy since there is a product for this! LOL...

I too heard that atrovent can dry secretions when I stitched to this new CF doc (my prior CF doc put me on it in another state)... But, she said I can feel free to stay on it if I want. I don't really see any difference personally, so I stayed on it cause I'm afraid of change. LOL

Anyway, I don't know how tolerance would work with CF drugs. I suppose maybe something like "resistance", which happens with overusing particular antibiotics, but as far as things that aim to open the airways, and have nothing to do with your infections directly, I don't know if your lungs would "get used to" something that has just one thing to do ... to open you up. I don't really see how that could happen with something like albuterol. I can see how you'd get sicker or have bad days when you didn't feel it helped you as much so need it more often, but that's all I've heard of.

I do know tolerance IS a real thing with regards to some psychological drugs, etc. where you'd need more of the med to get the same benefit the longer you use it, but it only happens with some drugs and I don't think things like bronchodialators fall into that category. I don't think we really have to worry about it much with things like inhaled meds. I think if you need something more or aren't feeling its effects, maybe your lungs just aren't where they were before and need more of the med to really open you up. I don't know...

Sorry for the long-winded answer. Its late. LOL