What's new
By:
Filters
Cystic Fibrosis Forum (EXP)

This is a sample guest message. Register a free account today to become a member! Once signed in, you'll be able to participate on this site by adding your own topics and posts, as well as connect with other members through your own private inbox!

Antibiotic Resistance

S

serendipity730

New member
Hi all,

So, since Nov.'08,I have consistantly cultured very resistant PA. In 11/08, I was having fevers and not responding to the abx I was on. The sputum culture showed that I was resistant to everything but Tobra and Colistin. I was treated with those two drugs, and my FEV1 recovered. Then, in April '09, a similar scenario played out - fevers, not responding to abx. My docs did a bronch and found I was now also resistant to Tobra. My FEV1 increased slightly from the beginning of the exacerbation, but stayed a good 10% pts below my baseline. Now, I am on my 3rd week of IV's. I am still having mild temp elevations (no higher than 99.8) and my FEV1 is another 5% pts below what it was after the April course of abx.

So, I guess my question for everyone is has anyone had a similar experience? I know that abx resistance patterns can change. Have you ever been resistant to almost everything, then become sensitive to mult. drugs again?

Thanks for your input!
 
S

serendipity730

New member
Hi all,

So, since Nov.'08,I have consistantly cultured very resistant PA. In 11/08, I was having fevers and not responding to the abx I was on. The sputum culture showed that I was resistant to everything but Tobra and Colistin. I was treated with those two drugs, and my FEV1 recovered. Then, in April '09, a similar scenario played out - fevers, not responding to abx. My docs did a bronch and found I was now also resistant to Tobra. My FEV1 increased slightly from the beginning of the exacerbation, but stayed a good 10% pts below my baseline. Now, I am on my 3rd week of IV's. I am still having mild temp elevations (no higher than 99.8) and my FEV1 is another 5% pts below what it was after the April course of abx.

So, I guess my question for everyone is has anyone had a similar experience? I know that abx resistance patterns can change. Have you ever been resistant to almost everything, then become sensitive to mult. drugs again?

Thanks for your input!
 
S

serendipity730

New member
Hi all,

So, since Nov.'08,I have consistantly cultured very resistant PA. In 11/08, I was having fevers and not responding to the abx I was on. The sputum culture showed that I was resistant to everything but Tobra and Colistin. I was treated with those two drugs, and my FEV1 recovered. Then, in April '09, a similar scenario played out - fevers, not responding to abx. My docs did a bronch and found I was now also resistant to Tobra. My FEV1 increased slightly from the beginning of the exacerbation, but stayed a good 10% pts below my baseline. Now, I am on my 3rd week of IV's. I am still having mild temp elevations (no higher than 99.8) and my FEV1 is another 5% pts below what it was after the April course of abx.

So, I guess my question for everyone is has anyone had a similar experience? I know that abx resistance patterns can change. Have you ever been resistant to almost everything, then become sensitive to mult. drugs again?

Thanks for your input!
 
S

serendipity730

New member
Hi all,

So, since Nov.'08,I have consistantly cultured very resistant PA. In 11/08, I was having fevers and not responding to the abx I was on. The sputum culture showed that I was resistant to everything but Tobra and Colistin. I was treated with those two drugs, and my FEV1 recovered. Then, in April '09, a similar scenario played out - fevers, not responding to abx. My docs did a bronch and found I was now also resistant to Tobra. My FEV1 increased slightly from the beginning of the exacerbation, but stayed a good 10% pts below my baseline. Now, I am on my 3rd week of IV's. I am still having mild temp elevations (no higher than 99.8) and my FEV1 is another 5% pts below what it was after the April course of abx.

So, I guess my question for everyone is has anyone had a similar experience? I know that abx resistance patterns can change. Have you ever been resistant to almost everything, then become sensitive to mult. drugs again?

Thanks for your input!
 
S

serendipity730

New member
Hi all,
<br />
<br />So, since Nov.'08,I have consistantly cultured very resistant PA. In 11/08, I was having fevers and not responding to the abx I was on. The sputum culture showed that I was resistant to everything but Tobra and Colistin. I was treated with those two drugs, and my FEV1 recovered. Then, in April '09, a similar scenario played out - fevers, not responding to abx. My docs did a bronch and found I was now also resistant to Tobra. My FEV1 increased slightly from the beginning of the exacerbation, but stayed a good 10% pts below my baseline. Now, I am on my 3rd week of IV's. I am still having mild temp elevations (no higher than 99.8) and my FEV1 is another 5% pts below what it was after the April course of abx.
<br />
<br />So, I guess my question for everyone is has anyone had a similar experience? I know that abx resistance patterns can change. Have you ever been resistant to almost everything, then become sensitive to mult. drugs again?
<br />
<br />Thanks for your input!
 
L

ladybug

New member
Mary,

I just wanted to say I'm in the same boat right now. I used to be very sensitive to lots of things and then over a one-year period my docs had me on way too many meds over way too long of a time (3 med combos for 2 weeks and then another 3-4 weeks of DIFFERENT med combos). This was done for two exacerbations and I'm pretty sure that is why now my p.a. is multi-resistant. I'm just speculating, but that's my guess since before this I had great coverage options.

Anyway, I suggest synergy testing if possible. It takes WEEKS to get back (like 6-8), so maybe they could do it on the stuff they just bronched? Just an idea.

All my best. I know this is very very frustrating and I hope you find some peace with it. I still haven't.

Also, hopefully others on here will have some insight into gaining back their sensitivities, as I do know it can happen, just not sure how often.
 
L

ladybug

New member
Mary,

I just wanted to say I'm in the same boat right now. I used to be very sensitive to lots of things and then over a one-year period my docs had me on way too many meds over way too long of a time (3 med combos for 2 weeks and then another 3-4 weeks of DIFFERENT med combos). This was done for two exacerbations and I'm pretty sure that is why now my p.a. is multi-resistant. I'm just speculating, but that's my guess since before this I had great coverage options.

Anyway, I suggest synergy testing if possible. It takes WEEKS to get back (like 6-8), so maybe they could do it on the stuff they just bronched? Just an idea.

All my best. I know this is very very frustrating and I hope you find some peace with it. I still haven't.

Also, hopefully others on here will have some insight into gaining back their sensitivities, as I do know it can happen, just not sure how often.
 
L

ladybug

New member
Mary,

I just wanted to say I'm in the same boat right now. I used to be very sensitive to lots of things and then over a one-year period my docs had me on way too many meds over way too long of a time (3 med combos for 2 weeks and then another 3-4 weeks of DIFFERENT med combos). This was done for two exacerbations and I'm pretty sure that is why now my p.a. is multi-resistant. I'm just speculating, but that's my guess since before this I had great coverage options.

Anyway, I suggest synergy testing if possible. It takes WEEKS to get back (like 6-8), so maybe they could do it on the stuff they just bronched? Just an idea.

All my best. I know this is very very frustrating and I hope you find some peace with it. I still haven't.

Also, hopefully others on here will have some insight into gaining back their sensitivities, as I do know it can happen, just not sure how often.
 
L

ladybug

New member
Mary,

I just wanted to say I'm in the same boat right now. I used to be very sensitive to lots of things and then over a one-year period my docs had me on way too many meds over way too long of a time (3 med combos for 2 weeks and then another 3-4 weeks of DIFFERENT med combos). This was done for two exacerbations and I'm pretty sure that is why now my p.a. is multi-resistant. I'm just speculating, but that's my guess since before this I had great coverage options.

Anyway, I suggest synergy testing if possible. It takes WEEKS to get back (like 6-8), so maybe they could do it on the stuff they just bronched? Just an idea.

All my best. I know this is very very frustrating and I hope you find some peace with it. I still haven't.

Also, hopefully others on here will have some insight into gaining back their sensitivities, as I do know it can happen, just not sure how often.
 
L

ladybug

New member
Mary,
<br />
<br />I just wanted to say I'm in the same boat right now. I used to be very sensitive to lots of things and then over a one-year period my docs had me on way too many meds over way too long of a time (3 med combos for 2 weeks and then another 3-4 weeks of DIFFERENT med combos). This was done for two exacerbations and I'm pretty sure that is why now my p.a. is multi-resistant. I'm just speculating, but that's my guess since before this I had great coverage options.
<br />
<br />Anyway, I suggest synergy testing if possible. It takes WEEKS to get back (like 6-8), so maybe they could do it on the stuff they just bronched? Just an idea.
<br />
<br />All my best. I know this is very very frustrating and I hope you find some peace with it. I still haven't.
<br />
<br />Also, hopefully others on here will have some insight into gaining back their sensitivities, as I do know it can happen, just not sure how often.
 
M

MicheleGazelle

New member
Someone who has been writing me privately since June has used the info here to deal with antibiotic resistant PA:
<a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.com/quinineandpseudomonas.shtml">http://healthgazelle.com/quinineandpseudomonas.shtml</a>

When this individual did need to go on antibiotics recently, I was told that the PA was sensitive to 15 drugs whereas previously it had only been sensitive to 7. In addition to consuming quinine, this individual also is taking a combo of sea salt, glyconutrients, and coconut oil.

Good luck with this.
 
M

MicheleGazelle

New member
Someone who has been writing me privately since June has used the info here to deal with antibiotic resistant PA:
<a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.com/quinineandpseudomonas.shtml">http://healthgazelle.com/quinineandpseudomonas.shtml</a>

When this individual did need to go on antibiotics recently, I was told that the PA was sensitive to 15 drugs whereas previously it had only been sensitive to 7. In addition to consuming quinine, this individual also is taking a combo of sea salt, glyconutrients, and coconut oil.

Good luck with this.
 
M

MicheleGazelle

New member
Someone who has been writing me privately since June has used the info here to deal with antibiotic resistant PA:
<a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.com/quinineandpseudomonas.shtml">http://healthgazelle.com/quinineandpseudomonas.shtml</a>

When this individual did need to go on antibiotics recently, I was told that the PA was sensitive to 15 drugs whereas previously it had only been sensitive to 7. In addition to consuming quinine, this individual also is taking a combo of sea salt, glyconutrients, and coconut oil.

Good luck with this.
 
M

MicheleGazelle

New member
Someone who has been writing me privately since June has used the info here to deal with antibiotic resistant PA:
<a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.com/quinineandpseudomonas.shtml">http://healthgazelle.com/quinineandpseudomonas.shtml</a>

When this individual did need to go on antibiotics recently, I was told that the PA was sensitive to 15 drugs whereas previously it had only been sensitive to 7. In addition to consuming quinine, this individual also is taking a combo of sea salt, glyconutrients, and coconut oil.

Good luck with this.
 
M

MicheleGazelle

New member
Someone who has been writing me privately since June has used the info here to deal with antibiotic resistant PA:
<br /><a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.com/quinineandpseudomonas.shtml">http://healthgazelle.com/quinineandpseudomonas.shtml</a>
<br />
<br />When this individual did need to go on antibiotics recently, I was told that the PA was sensitive to 15 drugs whereas previously it had only been sensitive to 7. In addition to consuming quinine, this individual also is taking a combo of sea salt, glyconutrients, and coconut oil.
<br />
<br />Good luck with this.
 
You must log in or register to reply here.
Top