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Antibiotiic resistent pathogens

Sakem

New member
I know antibiotics are essential in treatment of CF infections, but I do feel that in some cases they are over used in some CF individuals, thus resulting in multi resistant bacteria.

<a target=_blank class=ftalternatingbarlinklarge href="http://www.sciencedaily.com/releases/2009/02/090204112248.htm">http://www.sciencedaily.com/re...09/02/090204112248.htm</a>
 

Sakem

New member
I know antibiotics are essential in treatment of CF infections, but I do feel that in some cases they are over used in some CF individuals, thus resulting in multi resistant bacteria.

<a target=_blank class=ftalternatingbarlinklarge href="http://www.sciencedaily.com/releases/2009/02/090204112248.htm">http://www.sciencedaily.com/re...09/02/090204112248.htm</a>
 

Sakem

New member
I know antibiotics are essential in treatment of CF infections, but I do feel that in some cases they are over used in some CF individuals, thus resulting in multi resistant bacteria.

<a target=_blank class=ftalternatingbarlinklarge href="http://www.sciencedaily.com/releases/2009/02/090204112248.htm">http://www.sciencedaily.com/re...09/02/090204112248.htm</a>
 

Sakem

New member
I know antibiotics are essential in treatment of CF infections, but I do feel that in some cases they are over used in some CF individuals, thus resulting in multi resistant bacteria.

<a target=_blank class=ftalternatingbarlinklarge href="http://www.sciencedaily.com/releases/2009/02/090204112248.htm">http://www.sciencedaily.com/re...09/02/090204112248.htm</a>
 

Sakem

New member
I know antibiotics are essential in treatment of CF infections, but I do feel that in some cases they are over used in some CF individuals, thus resulting in multi resistant bacteria.
<br />
<br /><a target=_blank class=ftalternatingbarlinklarge href="http://www.sciencedaily.com/releases/2009/02/090204112248.htm">http://www.sciencedaily.com/re...09/02/090204112248.htm</a>
 

kitomd21

New member
I posted this email response in another thread regarding the same technology....

Dear Katie,

First of all, please know that my associates at NanoBio join me in
desiring the very best for your daughters' progress. In regard your
inquiry, our technology employs high-energy, oil-in-water emulsions to
kill the targeted organism. In appearance and feel, a nanoemulsion is a
thin white liquid, very similar to skim milk. The unique aspect of
products derived from the company's NanoStat technology is that, unlike
currently available therapies, NanoBio's treatments are antibiotic free
and selectively toxic to microbes while non-irritating to skin and
mucous membranes:
<a target=_blank class=ftalternatingbarlinklarge href="http://www.nanobio.com/Platform-Technology/Mechanism-of-Action.html
">http://www.nanobio.com/Platfor...hanism-of-Action.html
</a>
As you may be aware, we are in the initial laboratory stages with the
development of our product for CF. We have yet to confirm that what we
see in the laboratory will be appropriate for use in man. Next steps in
the long development pathway and prior to initiation of a Phase I
clinical trial will be determined by results from additional laboratory
studies and FDA approval.

We have expectations that products that are in development by NanoBio as
well as several other organizations should make meaningful contributions
to the quality of life for CF patients. Treatment options have expanded
significantly over the last 30 years that I have been involved in the
medical industry and undoubtedly, progress will continue.

I will be happy to address other questions that you may have in the
future. In addition, more information on NanoBio and our drug
development programs are described on the NanoBio web site:
www.nanobio.com

Sincere best wishes,

John Coffey

____________________________

John F. Coffey, Jr.
Vice President Business Development
NanoBio Corporation
2311 Green Road, Suite A 48105
Ann Arbor, MI
www.nanobio.com
 

kitomd21

New member
I posted this email response in another thread regarding the same technology....

Dear Katie,

First of all, please know that my associates at NanoBio join me in
desiring the very best for your daughters' progress. In regard your
inquiry, our technology employs high-energy, oil-in-water emulsions to
kill the targeted organism. In appearance and feel, a nanoemulsion is a
thin white liquid, very similar to skim milk. The unique aspect of
products derived from the company's NanoStat technology is that, unlike
currently available therapies, NanoBio's treatments are antibiotic free
and selectively toxic to microbes while non-irritating to skin and
mucous membranes:
<a target=_blank class=ftalternatingbarlinklarge href="http://www.nanobio.com/Platform-Technology/Mechanism-of-Action.html
">http://www.nanobio.com/Platfor...hanism-of-Action.html
</a>
As you may be aware, we are in the initial laboratory stages with the
development of our product for CF. We have yet to confirm that what we
see in the laboratory will be appropriate for use in man. Next steps in
the long development pathway and prior to initiation of a Phase I
clinical trial will be determined by results from additional laboratory
studies and FDA approval.

We have expectations that products that are in development by NanoBio as
well as several other organizations should make meaningful contributions
to the quality of life for CF patients. Treatment options have expanded
significantly over the last 30 years that I have been involved in the
medical industry and undoubtedly, progress will continue.

I will be happy to address other questions that you may have in the
future. In addition, more information on NanoBio and our drug
development programs are described on the NanoBio web site:
www.nanobio.com

Sincere best wishes,

John Coffey

____________________________

John F. Coffey, Jr.
Vice President Business Development
NanoBio Corporation
2311 Green Road, Suite A 48105
Ann Arbor, MI
www.nanobio.com
 

kitomd21

New member
I posted this email response in another thread regarding the same technology....

Dear Katie,

First of all, please know that my associates at NanoBio join me in
desiring the very best for your daughters' progress. In regard your
inquiry, our technology employs high-energy, oil-in-water emulsions to
kill the targeted organism. In appearance and feel, a nanoemulsion is a
thin white liquid, very similar to skim milk. The unique aspect of
products derived from the company's NanoStat technology is that, unlike
currently available therapies, NanoBio's treatments are antibiotic free
and selectively toxic to microbes while non-irritating to skin and
mucous membranes:
<a target=_blank class=ftalternatingbarlinklarge href="http://www.nanobio.com/Platform-Technology/Mechanism-of-Action.html
">http://www.nanobio.com/Platfor...hanism-of-Action.html
</a>
As you may be aware, we are in the initial laboratory stages with the
development of our product for CF. We have yet to confirm that what we
see in the laboratory will be appropriate for use in man. Next steps in
the long development pathway and prior to initiation of a Phase I
clinical trial will be determined by results from additional laboratory
studies and FDA approval.

We have expectations that products that are in development by NanoBio as
well as several other organizations should make meaningful contributions
to the quality of life for CF patients. Treatment options have expanded
significantly over the last 30 years that I have been involved in the
medical industry and undoubtedly, progress will continue.

I will be happy to address other questions that you may have in the
future. In addition, more information on NanoBio and our drug
development programs are described on the NanoBio web site:
www.nanobio.com

Sincere best wishes,

John Coffey

____________________________

John F. Coffey, Jr.
Vice President Business Development
NanoBio Corporation
2311 Green Road, Suite A 48105
Ann Arbor, MI
www.nanobio.com
 

kitomd21

New member
I posted this email response in another thread regarding the same technology....

Dear Katie,

First of all, please know that my associates at NanoBio join me in
desiring the very best for your daughters' progress. In regard your
inquiry, our technology employs high-energy, oil-in-water emulsions to
kill the targeted organism. In appearance and feel, a nanoemulsion is a
thin white liquid, very similar to skim milk. The unique aspect of
products derived from the company's NanoStat technology is that, unlike
currently available therapies, NanoBio's treatments are antibiotic free
and selectively toxic to microbes while non-irritating to skin and
mucous membranes:
<a target=_blank class=ftalternatingbarlinklarge href="http://www.nanobio.com/Platform-Technology/Mechanism-of-Action.html
">http://www.nanobio.com/Platfor...hanism-of-Action.html
</a>
As you may be aware, we are in the initial laboratory stages with the
development of our product for CF. We have yet to confirm that what we
see in the laboratory will be appropriate for use in man. Next steps in
the long development pathway and prior to initiation of a Phase I
clinical trial will be determined by results from additional laboratory
studies and FDA approval.

We have expectations that products that are in development by NanoBio as
well as several other organizations should make meaningful contributions
to the quality of life for CF patients. Treatment options have expanded
significantly over the last 30 years that I have been involved in the
medical industry and undoubtedly, progress will continue.

I will be happy to address other questions that you may have in the
future. In addition, more information on NanoBio and our drug
development programs are described on the NanoBio web site:
www.nanobio.com

Sincere best wishes,

John Coffey

____________________________

John F. Coffey, Jr.
Vice President Business Development
NanoBio Corporation
2311 Green Road, Suite A 48105
Ann Arbor, MI
www.nanobio.com
 

kitomd21

New member
I posted this email response in another thread regarding the same technology....
<br />
<br />Dear Katie,
<br />
<br />First of all, please know that my associates at NanoBio join me in
<br />desiring the very best for your daughters' progress. In regard your
<br />inquiry, our technology employs high-energy, oil-in-water emulsions to
<br />kill the targeted organism. In appearance and feel, a nanoemulsion is a
<br />thin white liquid, very similar to skim milk. The unique aspect of
<br />products derived from the company's NanoStat technology is that, unlike
<br />currently available therapies, NanoBio's treatments are antibiotic free
<br />and selectively toxic to microbes while non-irritating to skin and
<br />mucous membranes:
<br /><a target=_blank class=ftalternatingbarlinklarge href="http://www.nanobio.com/Platform-Technology/Mechanism-of-Action.html
">http://www.nanobio.com/Platfor...hanism-of-Action.html
</a><br />
<br />As you may be aware, we are in the initial laboratory stages with the
<br />development of our product for CF. We have yet to confirm that what we
<br />see in the laboratory will be appropriate for use in man. Next steps in
<br />the long development pathway and prior to initiation of a Phase I
<br />clinical trial will be determined by results from additional laboratory
<br />studies and FDA approval.
<br />
<br />We have expectations that products that are in development by NanoBio as
<br />well as several other organizations should make meaningful contributions
<br />to the quality of life for CF patients. Treatment options have expanded
<br />significantly over the last 30 years that I have been involved in the
<br />medical industry and undoubtedly, progress will continue.
<br />
<br />I will be happy to address other questions that you may have in the
<br />future. In addition, more information on NanoBio and our drug
<br />development programs are described on the NanoBio web site:
<br />www.nanobio.com
<br />
<br />Sincere best wishes,
<br />
<br />John Coffey
<br />
<br />____________________________
<br />
<br />John F. Coffey, Jr.
<br />Vice President Business Development
<br />NanoBio Corporation
<br />2311 Green Road, Suite A 48105
<br />Ann Arbor, MI
<br />www.nanobio.com
 

kitomd21

New member
The other thread didn't generate much response....perhaps because there have been so many "promising" therapies in the pipeline that haven't panned out? Still being relatively new to the CF community, do studies and promising therapies come along so frequently that many know not to get their hopes up? I'm just curious as to why this particular treatment isn't generating more buzz.....
 

kitomd21

New member
The other thread didn't generate much response....perhaps because there have been so many "promising" therapies in the pipeline that haven't panned out? Still being relatively new to the CF community, do studies and promising therapies come along so frequently that many know not to get their hopes up? I'm just curious as to why this particular treatment isn't generating more buzz.....
 

kitomd21

New member
The other thread didn't generate much response....perhaps because there have been so many "promising" therapies in the pipeline that haven't panned out? Still being relatively new to the CF community, do studies and promising therapies come along so frequently that many know not to get their hopes up? I'm just curious as to why this particular treatment isn't generating more buzz.....
 

kitomd21

New member
The other thread didn't generate much response....perhaps because there have been so many "promising" therapies in the pipeline that haven't panned out? Still being relatively new to the CF community, do studies and promising therapies come along so frequently that many know not to get their hopes up? I'm just curious as to why this particular treatment isn't generating more buzz.....
 

kitomd21

New member
The other thread didn't generate much response....perhaps because there have been so many "promising" therapies in the pipeline that haven't panned out? Still being relatively new to the CF community, do studies and promising therapies come along so frequently that many know not to get their hopes up? I'm just curious as to why this particular treatment isn't generating more buzz.....
 

jdubbs

New member
I agree that this development sounds exciting, but I think our optimism needs to be a guarded optimism. Take gene therapy for example. While theory suggested it would be a life saver, the logistics of the human body have stymied researchers so far. This emulsion has yet to be tested in human lungs. Until it's proven safe and effective in vivo, it's just another arm of CF research. In my opinion, it will probably have some complications, which may or may not be deal breakers. Also, even if the emulsion lives up to the hope, it will be years before its available to us. All that said, I'm definitely excited about the prospect and will be following the trials as they unfold. Thanks for posting Coffey's email by the way, I think it's cool you emailed him.
 

jdubbs

New member
I agree that this development sounds exciting, but I think our optimism needs to be a guarded optimism. Take gene therapy for example. While theory suggested it would be a life saver, the logistics of the human body have stymied researchers so far. This emulsion has yet to be tested in human lungs. Until it's proven safe and effective in vivo, it's just another arm of CF research. In my opinion, it will probably have some complications, which may or may not be deal breakers. Also, even if the emulsion lives up to the hope, it will be years before its available to us. All that said, I'm definitely excited about the prospect and will be following the trials as they unfold. Thanks for posting Coffey's email by the way, I think it's cool you emailed him.
 

jdubbs

New member
I agree that this development sounds exciting, but I think our optimism needs to be a guarded optimism. Take gene therapy for example. While theory suggested it would be a life saver, the logistics of the human body have stymied researchers so far. This emulsion has yet to be tested in human lungs. Until it's proven safe and effective in vivo, it's just another arm of CF research. In my opinion, it will probably have some complications, which may or may not be deal breakers. Also, even if the emulsion lives up to the hope, it will be years before its available to us. All that said, I'm definitely excited about the prospect and will be following the trials as they unfold. Thanks for posting Coffey's email by the way, I think it's cool you emailed him.
 

jdubbs

New member
I agree that this development sounds exciting, but I think our optimism needs to be a guarded optimism. Take gene therapy for example. While theory suggested it would be a life saver, the logistics of the human body have stymied researchers so far. This emulsion has yet to be tested in human lungs. Until it's proven safe and effective in vivo, it's just another arm of CF research. In my opinion, it will probably have some complications, which may or may not be deal breakers. Also, even if the emulsion lives up to the hope, it will be years before its available to us. All that said, I'm definitely excited about the prospect and will be following the trials as they unfold. Thanks for posting Coffey's email by the way, I think it's cool you emailed him.
 

jdubbs

New member
I agree that this development sounds exciting, but I think our optimism needs to be a guarded optimism. Take gene therapy for example. While theory suggested it would be a life saver, the logistics of the human body have stymied researchers so far. This emulsion has yet to be tested in human lungs. Until it's proven safe and effective in vivo, it's just another arm of CF research. In my opinion, it will probably have some complications, which may or may not be deal breakers. Also, even if the emulsion lives up to the hope, it will be years before its available to us. All that said, I'm definitely excited about the prospect and will be following the trials as they unfold. Thanks for posting Coffey's email by the way, I think it's cool you emailed him.
 
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