Melissa,I've been on Vancomycin off and on over the last 14 years. Watch out for what is called Red Man's syndrome. Symptoms of this include itching ( i itched from head to toe, and I mean every in between) and you may get red kind of like a rash. I have to do benadryl (50mg) before each dose. If you start itching, tell the nurse right away and they will stop the dose and inject benadryl into your iv ( this should take care of it for you) then they will restart your dose. They can also run vancomycin over a long period of time, i think they can run it in up to over a 4 hour period, this would help on the symtoms too. SInce i take benadryl they only have to run iti in over 90 minutes for me. Please let me know how your experience goes! Feel free to email me cfcndlelady@aol.com.Caren 31w/cf