Hi my daughter colonized with aspergillous about two and a half years ago. When the doctors suspected that she was having allergic symptoms to it they put her on Sporonox. After a few months they put her on a low dose prednisone for about 6 months, maybe less. As time goes by, it all blurs together. Anyhow, they weined her off the prednisone, rechecked her levels and they were extremely low. She has been off the Sporonox and Prednisone for almost two years now. So far now problems/symptoms have returned. I have to say, both my husband and I were not too keen on the prednisone deal. But after some discussion and seeing all the trouble the aspergillous was causing we decided to go with it as long as it was not going to be longer than 6 months and that it was indeed low. She took it first every day for about a week or so, then every other day, then maintained it for every three days (or something like that) for a while, then it was lowered again to like twice a week until they stopped it. All the while taking the sporonox. So far so good. I was told that aspergillous is in many CF patients but that it only causes problems to those that have an allergic reaction to it. Hope this helpsLiza