I viciously dose myself with Creon 20. 1 enzyme per 5 grams of fat is the only quantity that seems to work for me. A few times, when I was in the hospital in Harrisburg, that hospital's pharmacy didn't have Creon, so I was stuck with Ultrase. Well, needless to say I had brutal diareahha the entire stay. (Which now that I think about it, could very well have been from all the antibiotic IVs they were forcefeeding me) When I got home I was sure to resort back to Creon, and my bowel movements were normal again.