<b> Azithromycin disrupts the information flow between Pseudomonas bacteria </b>
The drug, azithromycin (AZM), has been found to curb pathogenic bacteria. AZM combats bacteria in the Pseudomonas aeruginosa family. Scientists have discovered that AZM prevents these bacteria from becoming aggressive and destructive. AZM blocks the mechanism used by the bacteria to "measure" how many of them there are in a particular environment. Unaware of their numbers and how strong they've already become, the pathogens, as a result, delay their big attack. AZM, which belongs to the macrolide group of drugs, is incapable of killing Pseudomonas aeruginosa, but helps to keep the pathogen relatively bengign, preventing it from moving into more antagonistic phase where it would begin attacking and destroying large sections of lung tissue.
<i>Source: CF Roundtable - Summer 2006 - Page 35</i>
The drug, azithromycin (AZM), has been found to curb pathogenic bacteria. AZM combats bacteria in the Pseudomonas aeruginosa family. Scientists have discovered that AZM prevents these bacteria from becoming aggressive and destructive. AZM blocks the mechanism used by the bacteria to "measure" how many of them there are in a particular environment. Unaware of their numbers and how strong they've already become, the pathogens, as a result, delay their big attack. AZM, which belongs to the macrolide group of drugs, is incapable of killing Pseudomonas aeruginosa, but helps to keep the pathogen relatively bengign, preventing it from moving into more antagonistic phase where it would begin attacking and destroying large sections of lung tissue.
<i>Source: CF Roundtable - Summer 2006 - Page 35</i>