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Pulmozyme

2

2005CFmom

Super Moderator
My husband has "non CF bronchiectasis" and is on Pulmozyme. He has only been on it a couple months and was put on a round of prednisone at the same time so I can't say for certain that the pulmozyme helps him.

He is still working on clearing old plugs in his lungs, but as soon as those clear we are hoping the pulmozyme will help keep them clear. His lung function was dropping, and this was basically the last med out there left to try.

As far as how pulomozyme works, I think it works on the DNA of the dead bacteria that combine with the mucus to make it extra thick/sticky. It breaks down the DNA and thins the mucus, so I don't think it matters wether or not you specifically have CF. Maybe just that you have similar bacteria as someone with CF.

But I also remember reading somewhere that they tested pulmozyme on patients with non-CF bronchiectasis and it was not very effective.

If I find that article, I'll post it for you.
 
2

2005CFmom

Super Moderator
My husband has "non CF bronchiectasis" and is on Pulmozyme. He has only been on it a couple months and was put on a round of prednisone at the same time so I can't say for certain that the pulmozyme helps him.

He is still working on clearing old plugs in his lungs, but as soon as those clear we are hoping the pulmozyme will help keep them clear. His lung function was dropping, and this was basically the last med out there left to try.

As far as how pulomozyme works, I think it works on the DNA of the dead bacteria that combine with the mucus to make it extra thick/sticky. It breaks down the DNA and thins the mucus, so I don't think it matters wether or not you specifically have CF. Maybe just that you have similar bacteria as someone with CF.

But I also remember reading somewhere that they tested pulmozyme on patients with non-CF bronchiectasis and it was not very effective.

If I find that article, I'll post it for you.
 
2

2005CFmom

Super Moderator
My husband has "non CF bronchiectasis" and is on Pulmozyme. He has only been on it a couple months and was put on a round of prednisone at the same time so I can't say for certain that the pulmozyme helps him.

He is still working on clearing old plugs in his lungs, but as soon as those clear we are hoping the pulmozyme will help keep them clear. His lung function was dropping, and this was basically the last med out there left to try.

As far as how pulomozyme works, I think it works on the DNA of the dead bacteria that combine with the mucus to make it extra thick/sticky. It breaks down the DNA and thins the mucus, so I don't think it matters wether or not you specifically have CF. Maybe just that you have similar bacteria as someone with CF.

But I also remember reading somewhere that they tested pulmozyme on patients with non-CF bronchiectasis and it was not very effective.

If I find that article, I'll post it for you.
 
2

2005CFmom

Super Moderator
My husband has "non CF bronchiectasis" and is on Pulmozyme. He has only been on it a couple months and was put on a round of prednisone at the same time so I can't say for certain that the pulmozyme helps him.

He is still working on clearing old plugs in his lungs, but as soon as those clear we are hoping the pulmozyme will help keep them clear. His lung function was dropping, and this was basically the last med out there left to try.

As far as how pulomozyme works, I think it works on the DNA of the dead bacteria that combine with the mucus to make it extra thick/sticky. It breaks down the DNA and thins the mucus, so I don't think it matters wether or not you specifically have CF. Maybe just that you have similar bacteria as someone with CF.

But I also remember reading somewhere that they tested pulmozyme on patients with non-CF bronchiectasis and it was not very effective.

If I find that article, I'll post it for you.
 
2

2005CFmom

Super Moderator
My husband has "non CF bronchiectasis" and is on Pulmozyme. He has only been on it a couple months and was put on a round of prednisone at the same time so I can't say for certain that the pulmozyme helps him.
<br />
<br />He is still working on clearing old plugs in his lungs, but as soon as those clear we are hoping the pulmozyme will help keep them clear. His lung function was dropping, and this was basically the last med out there left to try.
<br />
<br />As far as how pulomozyme works, I think it works on the DNA of the dead bacteria that combine with the mucus to make it extra thick/sticky. It breaks down the DNA and thins the mucus, so I don't think it matters wether or not you specifically have CF. Maybe just that you have similar bacteria as someone with CF.
<br />
<br />But I also remember reading somewhere that they tested pulmozyme on patients with non-CF bronchiectasis and it was not very effective.
<br />
<br />If I find that article, I'll post it for you.
<br />
<br />
 
N

Nightwriter

New member
I should have looked up the research before I replied. Sorry. My bad.

Pulmozyme is sure made out of weird stuff. Chinese Hamster Overies. I couldn't have made up a funnier source. They make it with Gentamyacin, although after processing, the antibiotic is no longer detectable. But the Hamster Overies are? Lol.

I found conflicting results on whether Pulmozyme is effective for bronchiectasis. But it is definitely a drug that is sometimes prescribed. These are old studies. I'm sure you can call Genentech and ask them for recent studies.

I always think anything that can't cause harm and can possibly help you is worth trying -- under a doctor's guidance.


<a target=_blank class=ftalternatingbarlinklarge href="http://www.pulmozyme.com/info/prescribing.jsp">http://www.pulmozyme.com/info/prescribing.jsp</a>
<a target=_blank class=ftalternatingbarlinklarge href="http://www.ncbi.nlm.nih.gov/pubmed/9596315
">http://www.ncbi.nlm.nih.gov/pubmed/9596315
</a><a target=_blank class=ftalternatingbarlinklarge href="http://www.gene.com/gene/news/press-releases/display.do?method=detail&id=4414
">http://www.gene.com/gene/news/...method=detail&id=4414
</a><a target=_blank class=ftalternatingbarlinklarge href="http://">Text</a>
 
N

Nightwriter

New member
I should have looked up the research before I replied. Sorry. My bad.

Pulmozyme is sure made out of weird stuff. Chinese Hamster Overies. I couldn't have made up a funnier source. They make it with Gentamyacin, although after processing, the antibiotic is no longer detectable. But the Hamster Overies are? Lol.

I found conflicting results on whether Pulmozyme is effective for bronchiectasis. But it is definitely a drug that is sometimes prescribed. These are old studies. I'm sure you can call Genentech and ask them for recent studies.

I always think anything that can't cause harm and can possibly help you is worth trying -- under a doctor's guidance.


<a target=_blank class=ftalternatingbarlinklarge href="http://www.pulmozyme.com/info/prescribing.jsp">http://www.pulmozyme.com/info/prescribing.jsp</a>
<a target=_blank class=ftalternatingbarlinklarge href="http://www.ncbi.nlm.nih.gov/pubmed/9596315
">http://www.ncbi.nlm.nih.gov/pubmed/9596315
</a><a target=_blank class=ftalternatingbarlinklarge href="http://www.gene.com/gene/news/press-releases/display.do?method=detail&id=4414
">http://www.gene.com/gene/news/...method=detail&id=4414
</a><a target=_blank class=ftalternatingbarlinklarge href="http://">Text</a>
 
N

Nightwriter

New member
I should have looked up the research before I replied. Sorry. My bad.

Pulmozyme is sure made out of weird stuff. Chinese Hamster Overies. I couldn't have made up a funnier source. They make it with Gentamyacin, although after processing, the antibiotic is no longer detectable. But the Hamster Overies are? Lol.

I found conflicting results on whether Pulmozyme is effective for bronchiectasis. But it is definitely a drug that is sometimes prescribed. These are old studies. I'm sure you can call Genentech and ask them for recent studies.

I always think anything that can't cause harm and can possibly help you is worth trying -- under a doctor's guidance.


<a target=_blank class=ftalternatingbarlinklarge href="http://www.pulmozyme.com/info/prescribing.jsp">http://www.pulmozyme.com/info/prescribing.jsp</a>
<a target=_blank class=ftalternatingbarlinklarge href="http://www.ncbi.nlm.nih.gov/pubmed/9596315
">http://www.ncbi.nlm.nih.gov/pubmed/9596315
</a><a target=_blank class=ftalternatingbarlinklarge href="http://www.gene.com/gene/news/press-releases/display.do?method=detail&id=4414
">http://www.gene.com/gene/news/...method=detail&id=4414
</a><a target=_blank class=ftalternatingbarlinklarge href="http://">Text</a>
 
N

Nightwriter

New member
I should have looked up the research before I replied. Sorry. My bad.

Pulmozyme is sure made out of weird stuff. Chinese Hamster Overies. I couldn't have made up a funnier source. They make it with Gentamyacin, although after processing, the antibiotic is no longer detectable. But the Hamster Overies are? Lol.

I found conflicting results on whether Pulmozyme is effective for bronchiectasis. But it is definitely a drug that is sometimes prescribed. These are old studies. I'm sure you can call Genentech and ask them for recent studies.

I always think anything that can't cause harm and can possibly help you is worth trying -- under a doctor's guidance.


<a target=_blank class=ftalternatingbarlinklarge href="http://www.pulmozyme.com/info/prescribing.jsp">http://www.pulmozyme.com/info/prescribing.jsp</a>
<a target=_blank class=ftalternatingbarlinklarge href="http://www.ncbi.nlm.nih.gov/pubmed/9596315
">http://www.ncbi.nlm.nih.gov/pubmed/9596315
</a><a target=_blank class=ftalternatingbarlinklarge href="http://www.gene.com/gene/news/press-releases/display.do?method=detail&id=4414
">http://www.gene.com/gene/news/...method=detail&id=4414
</a><a target=_blank class=ftalternatingbarlinklarge href="http://">Text</a>
 
N

Nightwriter

New member
I should have looked up the research before I replied. Sorry. My bad.
<br />
<br />Pulmozyme is sure made out of weird stuff. Chinese Hamster Overies. I couldn't have made up a funnier source. They make it with Gentamyacin, although after processing, the antibiotic is no longer detectable. But the Hamster Overies are? Lol.
<br />
<br />I found conflicting results on whether Pulmozyme is effective for bronchiectasis. But it is definitely a drug that is sometimes prescribed. These are old studies. I'm sure you can call Genentech and ask them for recent studies.
<br />
<br />I always think anything that can't cause harm and can possibly help you is worth trying -- under a doctor's guidance.
<br />
<br />
<br /><a target=_blank class=ftalternatingbarlinklarge href="http://www.pulmozyme.com/info/prescribing.jsp">http://www.pulmozyme.com/info/prescribing.jsp</a>
<br /><a target=_blank class=ftalternatingbarlinklarge href="http://www.ncbi.nlm.nih.gov/pubmed/9596315
">http://www.ncbi.nlm.nih.gov/pubmed/9596315
</a><br /><a target=_blank class=ftalternatingbarlinklarge href="http://www.gene.com/gene/news/press-releases/display.do?method=detail&id=4414
">http://www.gene.com/gene/news/...method=detail&id=4414
</a><br /><a target=_blank class=ftalternatingbarlinklarge href="http://">Text</a>
 
J

Juliet

New member
Pulmozyme is an enzyme which breaks down the long strands of dead RNA from the infections in our lungs. The RNA is left behind after our immune system kills the infections.

I was dxd with bronchectasis as a teenager. My regular doctor first sent me to the CF clinic because as someone with bronchectasis (and also MAC) he thought I could benefit from some of the newer CF drugs, one of them being Pulmozyme. I discussed that with the CF doc but hadn't yet started it. The CF center did however send my blood out for genetic testing and what came back, but a CF diagnosis! Nobody expected that at 43 years of age and overweight as I am.

Point is, if you've had some infections and plugging and mucus buildup there is a chance Pulmozyme could help you even if you don't have CF. ~Juliet
 
J

Juliet

New member
Pulmozyme is an enzyme which breaks down the long strands of dead RNA from the infections in our lungs. The RNA is left behind after our immune system kills the infections.

I was dxd with bronchectasis as a teenager. My regular doctor first sent me to the CF clinic because as someone with bronchectasis (and also MAC) he thought I could benefit from some of the newer CF drugs, one of them being Pulmozyme. I discussed that with the CF doc but hadn't yet started it. The CF center did however send my blood out for genetic testing and what came back, but a CF diagnosis! Nobody expected that at 43 years of age and overweight as I am.

Point is, if you've had some infections and plugging and mucus buildup there is a chance Pulmozyme could help you even if you don't have CF. ~Juliet
 
J

Juliet

New member
Pulmozyme is an enzyme which breaks down the long strands of dead RNA from the infections in our lungs. The RNA is left behind after our immune system kills the infections.

I was dxd with bronchectasis as a teenager. My regular doctor first sent me to the CF clinic because as someone with bronchectasis (and also MAC) he thought I could benefit from some of the newer CF drugs, one of them being Pulmozyme. I discussed that with the CF doc but hadn't yet started it. The CF center did however send my blood out for genetic testing and what came back, but a CF diagnosis! Nobody expected that at 43 years of age and overweight as I am.

Point is, if you've had some infections and plugging and mucus buildup there is a chance Pulmozyme could help you even if you don't have CF. ~Juliet
 
J

Juliet

New member
Pulmozyme is an enzyme which breaks down the long strands of dead RNA from the infections in our lungs. The RNA is left behind after our immune system kills the infections.

I was dxd with bronchectasis as a teenager. My regular doctor first sent me to the CF clinic because as someone with bronchectasis (and also MAC) he thought I could benefit from some of the newer CF drugs, one of them being Pulmozyme. I discussed that with the CF doc but hadn't yet started it. The CF center did however send my blood out for genetic testing and what came back, but a CF diagnosis! Nobody expected that at 43 years of age and overweight as I am.

Point is, if you've had some infections and plugging and mucus buildup there is a chance Pulmozyme could help you even if you don't have CF. ~Juliet
 
J

Juliet

New member
Pulmozyme is an enzyme which breaks down the long strands of dead RNA from the infections in our lungs. The RNA is left behind after our immune system kills the infections.
<br />
<br />I was dxd with bronchectasis as a teenager. My regular doctor first sent me to the CF clinic because as someone with bronchectasis (and also MAC) he thought I could benefit from some of the newer CF drugs, one of them being Pulmozyme. I discussed that with the CF doc but hadn't yet started it. The CF center did however send my blood out for genetic testing and what came back, but a CF diagnosis! Nobody expected that at 43 years of age and overweight as I am.
<br />
<br />Point is, if you've had some infections and plugging and mucus buildup there is a chance Pulmozyme could help you even if you don't have CF. ~Juliet
 
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