I am a 28 yr. old female with cf. I have multiple psuedamonouses and a lot of resistancy factors. According to the synergy studies done at columbia, I still should be responding to tobrymiacin and ceftazadime combination. However, the last two times I have done the three week course of antibiotics, I start feeling about halfway through them and directly after they are over, like I am completely tight chested, have trouble breathing, and feel extremely tired and unhungry. Last time this went away after sometime and the treatment was for the most part successful. Now it is happening again with this treatment and I want to know if this is something others are experiencing aswell?