I'm sorry to keep posting about HTS...and my questions have most likely been answered time and time again at some point on this forum, but, how has HTS affected your lung infections and/or hospital stays? Have you noticed a remarkable difference? Have bacterial strains become more affected by medications since starting HTS? I'm excited at the prospect of starting my daughter on HTS as there really couldn't be a more benign medication in terms of side effects! I'm also excited about Denufosol but wonder if the activated alternate ion channel will become less affected by the medication over time...I don't know anything about Denufosol other than what its method of action is...but I do worry about sensitivity issues over time. HTS seems like its results will remain consistent as long it is used. Has anyone else heard of Denufosol sensitivity diminishment concerns?