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Running out of effective oral ABXs (Resistance)

N

nick9742

New member
I have cultured MRSA for probably 10 years now (since my first sinus surgery) and it was very sensitive for years to Cipro and Tetracycline. I was on Tetra every day for about 2 years. Now it's resistant. I've heard of Doxycycline but I don't know if this will have cross-resistance or not. I have been on all the conventional ones and the only things that help even a little are Bactrim, Ketek, and Zyvox.

Anyway, I'm having a flare up (tight chest, SOB, lots of coughing, low grade fever) so I'm going to the doctor tomorrow. I just got off of IV Vanc 2 weeks ago so wanted to try something oral first.

Really, I just wanted to ask you guys if you have had any luck with any certain combinations or maybe something that isn't prescribed as often as other standard ones. I really like Zyvox but my insurance won't cover it, and I can't afford the 3 weeks I stay on it.

Just wanted something to maybe suggest tomorrow because if not I'm usually put on combo of Bactrim & Ketek which isn't helping much anymore.

Thanks!
 
N

nick9742

New member
I have cultured MRSA for probably 10 years now (since my first sinus surgery) and it was very sensitive for years to Cipro and Tetracycline. I was on Tetra every day for about 2 years. Now it's resistant. I've heard of Doxycycline but I don't know if this will have cross-resistance or not. I have been on all the conventional ones and the only things that help even a little are Bactrim, Ketek, and Zyvox.

Anyway, I'm having a flare up (tight chest, SOB, lots of coughing, low grade fever) so I'm going to the doctor tomorrow. I just got off of IV Vanc 2 weeks ago so wanted to try something oral first.

Really, I just wanted to ask you guys if you have had any luck with any certain combinations or maybe something that isn't prescribed as often as other standard ones. I really like Zyvox but my insurance won't cover it, and I can't afford the 3 weeks I stay on it.

Just wanted something to maybe suggest tomorrow because if not I'm usually put on combo of Bactrim & Ketek which isn't helping much anymore.

Thanks!
 
N

nick9742

New member
I have cultured MRSA for probably 10 years now (since my first sinus surgery) and it was very sensitive for years to Cipro and Tetracycline. I was on Tetra every day for about 2 years. Now it's resistant. I've heard of Doxycycline but I don't know if this will have cross-resistance or not. I have been on all the conventional ones and the only things that help even a little are Bactrim, Ketek, and Zyvox.

Anyway, I'm having a flare up (tight chest, SOB, lots of coughing, low grade fever) so I'm going to the doctor tomorrow. I just got off of IV Vanc 2 weeks ago so wanted to try something oral first.

Really, I just wanted to ask you guys if you have had any luck with any certain combinations or maybe something that isn't prescribed as often as other standard ones. I really like Zyvox but my insurance won't cover it, and I can't afford the 3 weeks I stay on it.

Just wanted something to maybe suggest tomorrow because if not I'm usually put on combo of Bactrim & Ketek which isn't helping much anymore.

Thanks!
 
N

nick9742

New member
I have cultured MRSA for probably 10 years now (since my first sinus surgery) and it was very sensitive for years to Cipro and Tetracycline. I was on Tetra every day for about 2 years. Now it's resistant. I've heard of Doxycycline but I don't know if this will have cross-resistance or not. I have been on all the conventional ones and the only things that help even a little are Bactrim, Ketek, and Zyvox.

Anyway, I'm having a flare up (tight chest, SOB, lots of coughing, low grade fever) so I'm going to the doctor tomorrow. I just got off of IV Vanc 2 weeks ago so wanted to try something oral first.

Really, I just wanted to ask you guys if you have had any luck with any certain combinations or maybe something that isn't prescribed as often as other standard ones. I really like Zyvox but my insurance won't cover it, and I can't afford the 3 weeks I stay on it.

Just wanted something to maybe suggest tomorrow because if not I'm usually put on combo of Bactrim & Ketek which isn't helping much anymore.

Thanks!
 
N

nick9742

New member
I have cultured MRSA for probably 10 years now (since my first sinus surgery) and it was very sensitive for years to Cipro and Tetracycline. I was on Tetra every day for about 2 years. Now it's resistant. I've heard of Doxycycline but I don't know if this will have cross-resistance or not. I have been on all the conventional ones and the only things that help even a little are Bactrim, Ketek, and Zyvox.
<br />
<br />Anyway, I'm having a flare up (tight chest, SOB, lots of coughing, low grade fever) so I'm going to the doctor tomorrow. I just got off of IV Vanc 2 weeks ago so wanted to try something oral first.
<br />
<br />Really, I just wanted to ask you guys if you have had any luck with any certain combinations or maybe something that isn't prescribed as often as other standard ones. I really like Zyvox but my insurance won't cover it, and I can't afford the 3 weeks I stay on it.
<br />
<br />Just wanted something to maybe suggest tomorrow because if not I'm usually put on combo of Bactrim & Ketek which isn't helping much anymore.
<br />
<br />Thanks!
 
J

jodijp

New member
Nick, I can certainly relate. <img src="i/expressions/face-icon-small-disgusted.gif" border="0"> I've had MRSA in every sputum culture for 8 years after my lung surgery. It has definitely been my nemisis and cause of the majority of my problems. Hmmm, seems we both picked up the darn cootie after surgery. <img src="i/expressions/face-icon-small-mad.gif" border="0">

I too have tried every thing including Vanco, that ruined my kidneys. I finally talked my doc into trying Zyvox for the first time this past Dec and Jan. I was on IVs for 3 weeks followed by 3 months of Bactrim everyday.

Guess what? It worked! <img src="i/expressions/face-icon-small-happy.gif" border="0"> The last 2 cultures have come up clear! <img src="i/expressions/face-icon-small-smile.gif" border="0"> I'm so happy but yet tentative in my happiness, knowing the booger could come back so easily.

But for now I'm rejoicing and am feeling much better. <img src="i/expressions/face-icon-small-happy.gif" border="0">

Good luck to you, hope you find a ABX combo that blasts that beast. <img src="i/expressions/devil.gif" border="0">
 
J

jodijp

New member
Nick, I can certainly relate. <img src="i/expressions/face-icon-small-disgusted.gif" border="0"> I've had MRSA in every sputum culture for 8 years after my lung surgery. It has definitely been my nemisis and cause of the majority of my problems. Hmmm, seems we both picked up the darn cootie after surgery. <img src="i/expressions/face-icon-small-mad.gif" border="0">

I too have tried every thing including Vanco, that ruined my kidneys. I finally talked my doc into trying Zyvox for the first time this past Dec and Jan. I was on IVs for 3 weeks followed by 3 months of Bactrim everyday.

Guess what? It worked! <img src="i/expressions/face-icon-small-happy.gif" border="0"> The last 2 cultures have come up clear! <img src="i/expressions/face-icon-small-smile.gif" border="0"> I'm so happy but yet tentative in my happiness, knowing the booger could come back so easily.

But for now I'm rejoicing and am feeling much better. <img src="i/expressions/face-icon-small-happy.gif" border="0">

Good luck to you, hope you find a ABX combo that blasts that beast. <img src="i/expressions/devil.gif" border="0">
 
J

jodijp

New member
Nick, I can certainly relate. <img src="i/expressions/face-icon-small-disgusted.gif" border="0"> I've had MRSA in every sputum culture for 8 years after my lung surgery. It has definitely been my nemisis and cause of the majority of my problems. Hmmm, seems we both picked up the darn cootie after surgery. <img src="i/expressions/face-icon-small-mad.gif" border="0">

I too have tried every thing including Vanco, that ruined my kidneys. I finally talked my doc into trying Zyvox for the first time this past Dec and Jan. I was on IVs for 3 weeks followed by 3 months of Bactrim everyday.

Guess what? It worked! <img src="i/expressions/face-icon-small-happy.gif" border="0"> The last 2 cultures have come up clear! <img src="i/expressions/face-icon-small-smile.gif" border="0"> I'm so happy but yet tentative in my happiness, knowing the booger could come back so easily.

But for now I'm rejoicing and am feeling much better. <img src="i/expressions/face-icon-small-happy.gif" border="0">

Good luck to you, hope you find a ABX combo that blasts that beast. <img src="i/expressions/devil.gif" border="0">
 
J

jodijp

New member
Nick, I can certainly relate. <img src="i/expressions/face-icon-small-disgusted.gif" border="0"> I've had MRSA in every sputum culture for 8 years after my lung surgery. It has definitely been my nemisis and cause of the majority of my problems. Hmmm, seems we both picked up the darn cootie after surgery. <img src="i/expressions/face-icon-small-mad.gif" border="0">

I too have tried every thing including Vanco, that ruined my kidneys. I finally talked my doc into trying Zyvox for the first time this past Dec and Jan. I was on IVs for 3 weeks followed by 3 months of Bactrim everyday.

Guess what? It worked! <img src="i/expressions/face-icon-small-happy.gif" border="0"> The last 2 cultures have come up clear! <img src="i/expressions/face-icon-small-smile.gif" border="0"> I'm so happy but yet tentative in my happiness, knowing the booger could come back so easily.

But for now I'm rejoicing and am feeling much better. <img src="i/expressions/face-icon-small-happy.gif" border="0">

Good luck to you, hope you find a ABX combo that blasts that beast. <img src="i/expressions/devil.gif" border="0">
 
J

jodijp

New member
Nick, I can certainly relate. <img src="i/expressions/face-icon-small-disgusted.gif" border="0"> I've had MRSA in every sputum culture for 8 years after my lung surgery. It has definitely been my nemisis and cause of the majority of my problems. Hmmm, seems we both picked up the darn cootie after surgery. <img src="i/expressions/face-icon-small-mad.gif" border="0">
<br />
<br />I too have tried every thing including Vanco, that ruined my kidneys. I finally talked my doc into trying Zyvox for the first time this past Dec and Jan. I was on IVs for 3 weeks followed by 3 months of Bactrim everyday.
<br />
<br />Guess what? It worked! <img src="i/expressions/face-icon-small-happy.gif" border="0"> The last 2 cultures have come up clear! <img src="i/expressions/face-icon-small-smile.gif" border="0"> I'm so happy but yet tentative in my happiness, knowing the booger could come back so easily.
<br />
<br />But for now I'm rejoicing and am feeling much better. <img src="i/expressions/face-icon-small-happy.gif" border="0">
<br />
<br />Good luck to you, hope you find a ABX combo that blasts that beast. <img src="i/expressions/devil.gif" border="0">
 
N

nick9742

New member
The Vanc has also ruined my kidneys. They're at about 40% right now. Was only able to tolerate it twice a day instead of the usual 4 times.

Glad that those worked for you! I have had Zyvox many times in the past and even it only got rid of it temporarily. I may ask to try a couple months of Bactrim anyway and see how it goes. Usually I'm only on it for 2 weeks.
 
N

nick9742

New member
The Vanc has also ruined my kidneys. They're at about 40% right now. Was only able to tolerate it twice a day instead of the usual 4 times.

Glad that those worked for you! I have had Zyvox many times in the past and even it only got rid of it temporarily. I may ask to try a couple months of Bactrim anyway and see how it goes. Usually I'm only on it for 2 weeks.
 
N

nick9742

New member
The Vanc has also ruined my kidneys. They're at about 40% right now. Was only able to tolerate it twice a day instead of the usual 4 times.

Glad that those worked for you! I have had Zyvox many times in the past and even it only got rid of it temporarily. I may ask to try a couple months of Bactrim anyway and see how it goes. Usually I'm only on it for 2 weeks.
 
N

nick9742

New member
The Vanc has also ruined my kidneys. They're at about 40% right now. Was only able to tolerate it twice a day instead of the usual 4 times.

Glad that those worked for you! I have had Zyvox many times in the past and even it only got rid of it temporarily. I may ask to try a couple months of Bactrim anyway and see how it goes. Usually I'm only on it for 2 weeks.
 
N

nick9742

New member
The Vanc has also ruined my kidneys. They're at about 40% right now. Was only able to tolerate it twice a day instead of the usual 4 times.
<br />
<br />Glad that those worked for you! I have had Zyvox many times in the past and even it only got rid of it temporarily. I may ask to try a couple months of Bactrim anyway and see how it goes. Usually I'm only on it for 2 weeks.
 
M

MCGrad2006

Guest
I have had the same problem lately. Bactrim doesnt do anything anymore, and Zyvox I feel like I am on all the time...ick. I tried "minocycline" if you would want to suggest that to your doctor. I had bad side effects so I had to stop, I dont knnow if it would be good for you though.

Hope you feel better soon!
 
M

MCGrad2006

Guest
I have had the same problem lately. Bactrim doesnt do anything anymore, and Zyvox I feel like I am on all the time...ick. I tried "minocycline" if you would want to suggest that to your doctor. I had bad side effects so I had to stop, I dont knnow if it would be good for you though.

Hope you feel better soon!
 
M

MCGrad2006

Guest
I have had the same problem lately. Bactrim doesnt do anything anymore, and Zyvox I feel like I am on all the time...ick. I tried "minocycline" if you would want to suggest that to your doctor. I had bad side effects so I had to stop, I dont knnow if it would be good for you though.

Hope you feel better soon!
 
M

MCGrad2006

Guest
I have had the same problem lately. Bactrim doesnt do anything anymore, and Zyvox I feel like I am on all the time...ick. I tried "minocycline" if you would want to suggest that to your doctor. I had bad side effects so I had to stop, I dont knnow if it would be good for you though.

Hope you feel better soon!
 
M

MCGrad2006

Guest
I have had the same problem lately. Bactrim doesnt do anything anymore, and Zyvox I feel like I am on all the time...ick. I tried "minocycline" if you would want to suggest that to your doctor. I had bad side effects so I had to stop, I dont knnow if it would be good for you though.
<br />
<br />Hope you feel better soon!
 
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