[taken from a <a target=_blank class=ftalternatingbarlinklarge href="http://www.cfcenter.net/living/may01/living-may01.htm}
">http://www.cfcenter.net/living...ving-may01.htm}
</a>
Soy, PIT, and CF: not a good partnership! (2001)
If you have been to see Dr. Pichurko in the last year and had the chance to meet with me, everyone's favorite dietitian, than you probably heard me mention the use of soy products. Soy and soybean-derived foods are becoming more and more popular in the United States . However, some research is telling us that CF patients may want to take caution with overuse of soy products. Soybeans have been grown over the last 50 years to increase the naturally occurring fungicide called phenyl isothiocyanate or PIT. Modern soybeans contain 2000-2500 parts per million of PIT where some old varieties only contained 1-2 parts per million of the same compound.
Why is this important for the CF patient? One of the systems that are affected by CF is the glutathione system, a natural antioxidant system within the body. Selenium, a mineral, plays an important role in this system by forming the glutathione peroxidase, a critical enzyme in the pathway. Without enough selenium, there is not enough of the critical enzyme and therefore it cannot function as well as an antioxidant.
PIT found in soybeans actually displaces selenium and in effect removes it from the body. PIT also interferes with the digestive enzymes as well. Because patients with CF commonly have problems with both of these systems, it is recommended that patients use caution when using modern soybean products in excess.
">http://www.cfcenter.net/living...ving-may01.htm}
</a>
Soy, PIT, and CF: not a good partnership! (2001)
If you have been to see Dr. Pichurko in the last year and had the chance to meet with me, everyone's favorite dietitian, than you probably heard me mention the use of soy products. Soy and soybean-derived foods are becoming more and more popular in the United States . However, some research is telling us that CF patients may want to take caution with overuse of soy products. Soybeans have been grown over the last 50 years to increase the naturally occurring fungicide called phenyl isothiocyanate or PIT. Modern soybeans contain 2000-2500 parts per million of PIT where some old varieties only contained 1-2 parts per million of the same compound.
Why is this important for the CF patient? One of the systems that are affected by CF is the glutathione system, a natural antioxidant system within the body. Selenium, a mineral, plays an important role in this system by forming the glutathione peroxidase, a critical enzyme in the pathway. Without enough selenium, there is not enough of the critical enzyme and therefore it cannot function as well as an antioxidant.
PIT found in soybeans actually displaces selenium and in effect removes it from the body. PIT also interferes with the digestive enzymes as well. Because patients with CF commonly have problems with both of these systems, it is recommended that patients use caution when using modern soybean products in excess.