I was just approved for telecommuting from my job, so I will get to work full time from home. My wife has been having health issues, and I have had to stay home to help her. My boss has been extremely supportive. So, I think it will work out well. I've been in my position for 8 years, so it's not like it's something I just found and got to do.
Something to look into though, is <a target=_blank class=ftalternatingbarlinklarge href="http://en.wikipedia.org/wiki/List_of_multi-level_marketing_companies">Network Marketing.</a> A good company with a great product is what to look for. Particularly a product new to the market. A strong web presence is also good, where you can present and purchase online.
Anyone can PM me if you would like to discuss further.