I have been on L-Lysine ( 4000 mg per day) for about a year now but not for any other reason than its ability to help control hemoptysis. I have never heard of it having ANY connection to glutathione. In fact i am also on oral glutathione 1500 mg per day. I have heard of NAC helping the body produce glutathione, but not L-Lysine, i would be interested to see that article....where did you read that? Well anyway..... like another poster said , why not just take Glutathione itself ?