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Sildenafil and vardenafil has been studied in mice with homozygous DF508 with some positive results. There are still some issues that need addressed, particularly dosing. I don't think it's been studied in humans yet.

Maybe there's an allergy component. The pollen count has been really high lately (yesterday it was 11.20/12 here).

Maybe there's an allergy component. The pollen count has been really high lately (yesterday it was 11.20/12 here).

I find the site lacking.

I find the site lacking.

<div class="FTQUOTE"><begin quote><em>Originally posted by: <strong>carly23</strong></em>they had to pick me up and place me on the stretcher and thought on the way to the hospital that there was air in my front right lung and i knew it was in my back so i was like no its my back but they stuck...

<div class="FTQUOTE"><begin quote><em>Originally posted by: <strong>carly23</strong></em>they had to pick me up and place me on the stretcher and thought on the way to the hospital that there was air in my front right lung and i knew it was in my back so i was like no its my back but they stuck...

Yeah I have to agree, PA is ubiquitous you don't need another CFer involved at all to expose yourself to it. Personally, I would ask the teacher if she cultures anything. If the answer isn't something like B cepacia, Achromobacter, really resistant mucoid PA or MRSA then I would say go for it...

Yeah I have to agree, PA is ubiquitous you don't need another CFer involved at all to expose yourself to it. Personally, I would ask the teacher if she cultures anything. If the answer isn't something like B cepacia, Achromobacter, really resistant mucoid PA or MRSA then I would say go for it...

I just got my first vest and it's a 105. I don't think it goes off unless it's on the home screen. Only having used it once, though, I could be wrong.

I just got my first vest and it's a 105. I don't think it goes off unless it's on the home screen. Only having used it once, though, I could be wrong.

^^^agree

^^^agree

Wow Bill, I didn't realize your FEV1 was that high. Really well done, man.

Wow Bill, I didn't realize your FEV1 was that high. Really well done, man.

I agree wholeheartedly with the exercise bit. I know a few people with similar numbers to yours (or lower) with a really good quality of life. As much exercise as you can tolerate would be a good place to start.

I agree wholeheartedly with the exercise bit. I know a few people with similar numbers to yours (or lower) with a really good quality of life. As much exercise as you can tolerate would be a good place to start.

Do you have any scientific evidence for this? As I stated before I have a class I and III and have an extremely mild presentation. The scientists studying epigenetics don't understand all the implications, yet here you are proclaiming something based on guesswork. Any sentence containing "I...

Do you have any scientific evidence for this? As I stated before I have a class I and III and have an extremely mild presentation. The scientists studying epigenetics don't understand all the implications, yet here you are proclaiming something based on guesswork. Any sentence containing "I...

I don't take any mucolytic agents. As for the genotype/phenotype bit, i would not be speculating on that kind of thing especially with someone who is not very familiar with the disease pathology. We really don't know much about epigenetics, and to say that a class V might produce a milder...